HBP: the pacing modality of the future?

HBP: the pacing modality of the future?

Why conduction system pacing is the most synchronized physiological pacing modality of the future

In a nutshell

Patients with a bradycardia (slow heart rate) or conduction system disease, can now be paced more effectively with a procedure referred to as His Bundle Pacing (HBP). The conduction system is stimulated directly, allowing both ventricles to contract simultaneously. This leads to better patient outcomes, and bypasses the risk of developing left bundle branch block, often the result of long-term traditional pacing. HBP is hailed as the ‘pacing of the future’.

The procedure can generally only be performed by an electrophysiologist. It requires a steep learning curve and often success rates may vary depending on patient anatomy and substrate. The technique is a very suitable alternative or adjunct to CRT (cardiac resynchronize therapy). However, the results of randomized controlled studies are pending, but the technique offers much promise.

Additional key points on HBP

Fig 1: Diagram – Implant procedure tips

  • His‐Purkinje conduction system pacing (HPCSP) in the form of His bundle pacing (HBP) and left bundle branch pacing (LBBP) allows normal left ventricular activation, thereby preventing the adverse consequences of right ventricular pacing.
  • HBP has been established for several years with centers from China, Europe, and North America reporting their experience.
  • There is international guidance as to how to implant such systems with the differing patterns of His bundle capture clearly described.
  • LBBP (left bundle branch block pacing) is a more recent innovation with potential advantages including improved pacing parameters.
  • HPCSP has been extensively studied in a variety of indications including cardiac resynchronization therapy, atrioventricular node ablation, and bradycardia pacing.
  • His bundle (HB) pacing is an established modality for achieving physiological pacing with a low risk of long‐term lead‐related complications.
  • Knowledge of the anatomy of the HB region and its variations is essential for successful implantation.
  • The development of specially designed lead and delivery tools has improved the feasibility and safety of HB pacing (HBP).
  • Newer delivery systems have further improved procedural outcomes.
  • Challenging implant cases can be successfully performed by reshaping the current sheaths, using a “sheath in sheath” technique or “two‐lead implantation technique.”
  • Special attention to the lead parameters at implant, programming, and follow‐up is eesential for successful long‐term outcomes with HBP.
  • Widespread use of HBP by electrophysiologists and further advances in dedicated delivery systems and leads are essential to further improve the effectiveness of the implantation.

More information

HIS Bundle Pacing Summary Slides